Shire Human Genetic Therapies
Business Challenge: Project Managing a Fix Ross Project
In 2005 Tranksaryotic Therapies, Inc. (TKT) of Cambridge, MA was acquired by Shire Pharmaceuticals Group plc resulting in the formation of Shire HGT. TKT gave Shire HGT significant expertise in the discovery, development, manufacturing and marketing of protein therapeutics.
TKT was a user of Ross ERP and in 2006 & 2007 Shire HGT implemented Ross ERP manufacturing, sales and financials. The implementation of Ross at Shire HGT was not a success, in particular the manufacturing implementation was poorly managed by the former services provider who lacked sufficient knowledge of Ross ERP and failed to provide proper training and transfer sufficient knowledge to Shire users.
As a result, master database elements were built with overly complex structures, adequate testing was not provided and a forced go live was executed that resulted in chaos for the business.
After a business review in early 2008 it was decided to re-implement Ross ERP through a Fix Ross project. Calvin Smucker was appointed as project manager of this re-implementation. In mid-2008, Calvin and his team set about fixing Ross. This was a three year project, but positive results were not only achieved in phases, but the first results were seen in a matter of months.
Phase 1 tackled the issue of the poorly implemented manufacturing system. The structuring of 30 plus stages within a recipe line was a gross misuse of the system and at the core of problems associated with inventory accuracy, untimely transactions and accounting variances.
Phase 2 followed immediately on the heels of the success of the initial effort with requests for additional improvements in other functional areas and for assistance with operational expansion in Europe.
Calvin’s role soon expanded to also include systems administration and management, including help desk support, user training, auditing, and systems validation.
Restructure the overall manufacturing process
Streamline specifications and recipes
Streamline job processing
Improve cost allocations and variance analysis
Correct master data and configuration setup
Update inventory processes and improve accuracy
Implement quality control enhancements
Improve Business Objects reporting
Material management improvements
Quality Control enhancements
Distribution controls and process enhancements
Implement cycle counting
Configure additional factories and warehouses
Job processing improvements
Lot sequence number management at the unit level
Streamlining European operations
Complex structuring of EU external freight distribution warehouses
Configuration for EU companies in Italy, Greece, Portugal, Turkey
New division for unique drug supply chain and finance requirements
Configuration for EU contract manufacturing
Sales Order automation across multiple companies and countries
Data Collection implementation
Finance improvements and modifications
Ross/SAP interface and data exchange
Ross Managed Services
Business Objects & SciQuest Managed Services
Biannual Financial Audits
System Validation (GMP)
Fix Ross was a huge success for Shire, allowing them to grow from 400 to 1200 staff and open a state-of-the-art facility in Lexington, MA. This was followed by the addition of yet another manufacturing location and a significant supply chain and operations expansion across both the US and Europe. This growth was in no small part due to the project management skills of Calvin Smucker who oversaw the project from day one until its completion.